Unipolar Depression
|
0.320 |
Biomarker
|
disease |
PSYGENET |
We also completed studies with humans on the association of polymorphisms in the AC7 gene with major depressive illness (unipolar depression) based on Diagnostic and Statistical Manual of Mental Disorders IV criteria.
|
17135423 |
2006 |
Unipolar Depression
|
0.320 |
Biomarker
|
disease |
PSYGENET |
This converging cross-species evidence implicates ADCY7 in the modulation of mood regulatory neural mechanisms and, possibly, risk for and pathophysiology of depression, together supporting a continuous dimensional approach to major depressive disorder and other affective disorders.
|
22264442 |
2012 |
Unipolar Depression
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We also completed studies with humans on the association of polymorphisms in the AC7 gene with major depressive illness (unipolar depression) based on Diagnostic and Statistical Manual of Mental Disorders IV criteria.
|
17135423 |
2006 |
Unipolar Depression
|
0.320 |
Biomarker
|
disease |
BEFREE |
This converging cross-species evidence implicates ADCY7 in the modulation of mood regulatory neural mechanisms and, possibly, risk for and pathophysiology of depression, together supporting a continuous dimensional approach to major depressive disorder and other affective disorders.
|
22264442 |
2012 |
Ulcerative Colitis
|
0.410 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
|
28067908 |
2017 |
Ulcerative Colitis
|
0.410 |
Biomarker
|
disease |
CTD_human |
We discovered a 0.6% frequency missense variant in ADCY7 that doubles the risk of ulcerative colitis.
|
28067910 |
2017 |
Ulcerative Colitis
|
0.410 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
|
26301688 |
2015 |
Ulcerative Colitis
|
0.410 |
GeneticVariation
|
disease |
GWASCAT |
We discovered a 0.6% frequency missense variant in ADCY7 that doubles the risk of ulcerative colitis.
|
28067910 |
2017 |
Ulcerative Colitis
|
0.410 |
GeneticVariation
|
disease |
BEFREE |
We discovered a 0.6% frequency missense variant in ADCY7 that doubles the risk of ulcerative colitis.
|
28067910 |
2017 |
Tumor Progression
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
Both PECAM1 and ADCY7 promoted tumor progression through the AKT pathway, showing the same molecular mechanism as CD300A.
|
29938007 |
2018 |
Tumor Progression
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
Adenylate cyclase 7 (AC7) has been reported to participate in various biological processes during cancer progression.
|
30366671 |
2018 |
Schizophrenia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Exome sequencing supports a de novo mutational paradigm for schizophrenia.
|
21822266 |
2011 |
Psoriasis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
|
26301688 |
2015 |
Polyarthritis, Juvenile, Rheumatoid Factor Positive
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
Polyarthritis, Juvenile, Rheumatoid Factor Negative
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
Mood Disorders
|
0.310 |
Biomarker
|
group |
BEFREE |
This converging cross-species evidence implicates ADCY7 in the modulation of mood regulatory neural mechanisms and, possibly, risk for and pathophysiology of depression, together supporting a continuous dimensional approach to major depressive disorder and other affective disorders.
|
22264442 |
2012 |
Mood Disorders
|
0.310 |
Biomarker
|
group |
PSYGENET |
This converging cross-species evidence implicates ADCY7 in the modulation of mood regulatory neural mechanisms and, possibly, risk for and pathophysiology of depression, together supporting a continuous dimensional approach to major depressive disorder and other affective disorders.
|
22264442 |
2012 |
Mental disorders
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Whether variations in ADCY7 and possible variations in other members of this gene family are underlying other psychiatric disorders remains to be studied.
|
9034014 |
1997 |
Mental disorders
|
0.020 |
GeneticVariation
|
group |
BEFREE |
We also completed studies with humans on the association of polymorphisms in the AC7 gene with major depressive illness (unipolar depression) based on Diagnostic and Statistical Manual of Mental Disorders IV criteria.
|
17135423 |
2006 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
BEFREE |
This converging cross-species evidence implicates ADCY7 in the modulation of mood regulatory neural mechanisms and, possibly, risk for and pathophysiology of depression, together supporting a continuous dimensional approach to major depressive disorder and other affective disorders.
|
22264442 |
2012 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
PSYGENET |
This converging cross-species evidence implicates ADCY7 in the modulation of mood regulatory neural mechanisms and, possibly, risk for and pathophysiology of depression, together supporting a continuous dimensional approach to major depressive disorder and other affective disorders.
|
22264442 |
2012 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
BEFREE |
Adenylyl cyclase 7 and neuropsychiatric disorders: A new target for depression?
|
30904753 |
2019 |
Major Depressive Disorder
|
0.320 |
Biomarker
|
disease |
PSYGENET |
We also completed studies with humans on the association of polymorphisms in the AC7 gene with major depressive illness (unipolar depression) based on Diagnostic and Statistical Manual of Mental Disorders IV criteria.
|
17135423 |
2006 |
Major Depressive Disorder
|
0.320 |
Biomarker
|
disease |
BEFREE |
This converging cross-species evidence implicates ADCY7 in the modulation of mood regulatory neural mechanisms and, possibly, risk for and pathophysiology of depression, together supporting a continuous dimensional approach to major depressive disorder and other affective disorders.
|
22264442 |
2012 |
Major Depressive Disorder
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We also completed studies with humans on the association of polymorphisms in the AC7 gene with major depressive illness (unipolar depression) based on Diagnostic and Statistical Manual of Mental Disorders IV criteria.
|
17135423 |
2006 |